World of Goo is probably the only Wii-to-PC port I've ever played.  As a 
port, it's basically seamless.  Maybe too much so.  It's effectively 
identical to the Wii version, which includes the complete lack of options 
such as resolution or volume control.  (These are possibly accessible in 
an ini file; I haven't checked.)  The precision of the mouse control was a 
welcome feature.  The game on the Wii is fun despite the shaky wiimote 
control.
 
The game just oozes atmosphere.  Gameplay and level design are clever.  My 
one disappointment is now it's over!  I suppose I'll have to try for all 
the OCD achievements (each level has an additional set of requirements to 
achieve an OCD award, such as a higher minimum number of goo to save or a 
time limit).